The study was conducted in routine clinic settings using nurses/medical assistants. These were tested with patient samples for the following analytes: occult blood, leukocytes, nitrite, protein, ketone, bilirubin, urobilinogen, specific gravity, pH, and glucose. To compare clinical results, each product was tested with approximately 200 test points using test strips from bottles that were both exposed and unexposed to humidity. This study analyzed Siemens’ MULTISTIX 10 SG urine reagent strips, Roche Diagnostics’ CHEMSTRIP 10 MD, and Diagnostic Test Group’s Clarity UROCHECK 10SG to determine product integrity after exposure to room air, a condition that can occur if the strip containers are not closed after use as directed by the manufacturer. A new feature provided with Siemens urinalysis strips used in combination with the Siemens CLINITEK Status+ Analyzer allows for the automatic detection of reagent strips that may have been affected by excess humidity. If strip bottles are not recapped or tightened completely, the contents can be exposed to humidity, potentially compromising the strip integrity and leading to reagent degradation and false results. The improper handling of strips, regardless of brand, can lead to false results and possible incorrect diagnosis. The integrity of urine strips is essential in obtaining accurate urinalysis test results.
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